NACAD

Across TCGA patient cohorts, NACAD RNA expression is significantly associated with the protein abundance of many other proteins, with 15,669 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NACAD-associated proteins across cancer lineages are VCAN, AEBP1, and FN1. Each is linked with NACAD in more than 6 cancer types. Because this analysis shows association rather than direction, both NACAD-to-partner and partner-to-NACAD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NACAD versus VCAN in OV, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NACAD→partner) and Y-score (partner→NACAD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	VCAN →	+1.000	+0.633	<.001	.008	3	7
PDAC	AEBP1 →	+0.699	+0.412	<.001	<.001	3	7
BRCA	FN1 →	+0.675	+0.484	<.001	<.001	3	7
GBM	MAP1A →	+0.530	+0.806	<.001	<.001	3	6
LSCC	MAP1LC3A →	+0.694	+0.447	<.001	.001	3	6
UCEC	PALLD →	+0.732	+0.608	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,669 associations by consensus.

NACAD vs VCAN — OV

Explore this scatter interactively →