NAALADL2

Across TCGA patient cohorts, NAALADL2 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,313 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NAALADL2-associated proteins across cancer lineages are PTPN1, C5AR1_S327, and CASP6. Each is linked with NAALADL2 in more than 5 cancer types. Because this analysis shows association rather than direction, both NAALADL2-to-partner and partner-to-NAALADL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NAALADL2 versus PTPN1 in CCRCC, with a Pearson correlation of -0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NAALADL2→partner) and Y-score (partner→NAALADL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PTPN1 →	-0.428	-0.478	<.001	<.001	3	6
COAD	C5AR1_S327 →	-0.865	-0.809	<.001	<.001	3	5
LSCC	CASP6 →	+0.388	+1.105	<.001	<.001	3	5
COAD	CRLF3 →	-0.342	-0.696	<.001	<.001	3	5
COAD	CTNNA1 →	+0.308	+0.641	<.001	<.001	3	5
GBM	DEF6 →	-0.465	-0.422	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,313 associations by consensus.

NAALADL2 vs PTPN1 — CCRCC

Explore this scatter interactively →