NAALADL2

Across TCGA patient cohorts, NAALADL2 mutation is significantly associated with the RNA expression of many other genes, with 5,854 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NAALADL2-associated genes across cancer lineages are LINC01707, LINC02672, and RNU4-14P. Each is linked with NAALADL2 in more than 2 cancer types. Because this analysis shows association rather than direction, both NAALADL2-to-partner and partner-to-NAALADL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01707 grouped by NAALADL2-low versus NAALADL2-high in ACC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAALADL2→partner) and Y-score (partner→NAALADL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	LINC01707 →	+0.084	+5.228	<.001	.005	3	3
ACC	LINC02672 →	+0.232	+4.887	<.001	.009	3	3
LUSC	RNU4-14P →	+0.296	+2.729	.008	.009	3	3
UCEC	VRK1 →	+0.490	+2.745	.002	<.001	3	3
UCEC	EZH2 →	+0.617	+2.222	<.001	<.001	3	3
UCEC	ANKMY2 →	+0.541	+2.568	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,854 associations by consensus.

LINC01707 by NAALADL2 expression — ACC

Explore this box plot interactively →