NAALADL2

Across TCGA cell cohorts, NAALADL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,512 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NAALADL2-associated GO terms across cancer lineages are Late endosome to lysosome transport, Cholesterol biosynthetic process via lathosterol, and Adenosine catabolic process. Each is linked with NAALADL2 in more than 7 cancer types. Because this analysis shows association rather than direction, both NAALADL2-to-partner and partner-to-NAALADL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Late endosome to lysosome transport grouped by NAALADL2-low versus NAALADL2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NAALADL2→partner) and Y-score (partner→NAALADL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Late endosome to lysosome transport →	+0.130	+1.110	.001	<.001	3	8
OVARY	Cholesterol biosynthetic process via lathosterol →	+0.142	+0.870	.001	.001	3	8
OESOPHAGUS	Adenosine catabolic process →	-1.245	-1.190	<.001	.001	3	8
BREAST	External encapsulating structure organization →	-0.071	-0.686	.006	.004	3	7
BLOOD_Lymphoma	Isopentenyl diphosphate biosynthetic process →	+0.148	+0.760	<.001	.001	3	7
BONE	Endosomal transport →	+0.072	+1.082	.001	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,512 associations by consensus.

Late endosome to lysosome transport by NAALADL2 expression — STOMACH

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