NAALADL1

Across TCGA cell cohorts, NAALADL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,566 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible NAALADL1-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Regulation of myoblast fusion. Each is linked with NAALADL1 in more than 6 cancer types. Because this analysis shows association rather than direction, both NAALADL1-to-partner and partner-to-NAALADL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by NAALADL1-low versus NAALADL1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NAALADL1→partner) and Y-score (partner→NAALADL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of myoblast fusion →	+0.103	+0.228	<.001	.009	3	7
BREAST	Negative regulation of syncytium formation by plasma membrane fusion →	+0.060	+0.286	.006	.008	3	7
LUNG_SCLC	Regulation of myoblast fusion →	+0.091	+1.933	<.001	.001	3	6
SOFT_TISSUE	Negative regulation of mRNA metabolic process →	+0.100	+0.747	<.001	.008	3	6
SOFT_TISSUE	Regulation of cytokinesis →	+0.090	+0.369	<.001	.005	3	6
UPPER_AERODIGESTIVE_TRACT	Negative regulation of mRNA catabolic process →	+0.054	+0.196	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,566 associations by consensus.

Negative regulation of myoblast fusion by NAALADL1 expression — BREAST

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