NAA50

Across TCGA patient cohorts, NAA50 mutation is significantly associated with the RNA expression of many other genes, with 1,442 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NAA50-associated genes across cancer lineages are RNU6-918P, NDUFAF2P1, and IGHV1-69D. Each is linked with NAA50 in more than 1 cancer types. Because this analysis shows association rather than direction, both NAA50-to-partner and partner-to-NAA50 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-918P grouped by NAA50-low versus NAA50-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAA50→partner) and Y-score (partner→NAA50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-918P →	+0.296	+2.572	<.001	.002	3	2
UCEC	NDUFAF2P1 →	+0.582	+1.858	<.001	.005	3	1
UCEC	IGHV1-69D →	+2.396	+2.747	<.001	<.001	3	1
UCEC	LINC01943 →	+0.446	+2.280	.001	.001	3	1
UCEC	RASSF1-AS1 →	+0.501	+3.839	<.001	<.001	3	1
UCEC	TAF7 →	+0.428	+2.190	.007	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,442 associations by consensus.

RNU6-918P by NAA50 expression — UCEC

Explore this box plot interactively →