NAA40

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NAA40 mutation is significantly associated with the RNA expression of many other genes, with 847 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NAA40-associated genes across cancer lineages are RN7SKP113, RNU6-38P, and PSAT1P4. Each is linked with NAA40 in more than 1 cancer types. Because this analysis shows association rather than direction, both NAA40-to-partner and partner-to-NAA40 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP113 grouped by NAA40-low versus NAA40-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAA40→partner) and Y-score (partner→NAA40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCARN7SKP113 →+0.143+7.640<.001.00932
BLCARNU6-38P →+0.908+7.640<.001.00932
UCECPSAT1P4 →+0.132+2.563.004<.00132
CESCEIF4A1P3 →+0.180+4.779.002.00132
UCECRN7SL342P →+0.167+2.298<.001.00632
BLCARNA5SP56 →+0.317+7.640<.001.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 847 associations by consensus.

RN7SKP113 by NAA40 expression — BLCA

Box plot of RN7SKP113 in NAA40-low vs NAA40-high samples in BLCA.

Explore this box plot interactively →

Exploration