Q-omics provides the consensus-scored RNU6-38P profile across patient tissues and cancer cell-line models. RNU6-38P expression is associated with patient survival in 12 of 34 cancer types, with the highest sampling consensus in ESCA. Additionally, RNU6-38P RNA expression shows 6,066 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight ESCA, and STAD as cancer lineages where RNU6-38P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes RNU6-38P survival associations across molecular data types. RNU6-38P RNA expression shows survival associations in the most cancer types (12). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

RNU6-38P data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	12	ESCA (63)	view →

This table ranks reproducible RNU6-38P RNA expression–survival associations across cancer types. High RNU6-38P expression shows unfavorable associations in ESCA, BRCA, LUAD, COAD and PAAD, but favorable associations in STAD. The ESCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .008). Together, the overview and detailed table identify ESCA as the clearest survival context for RNU6-38P RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Tertile	IV	0.095	0.512	.008	63	view →
BRCA	OS	Tertile	II,III,IV	0.833	0.958	<.001	60	view →
LUAD	OS	Tertile	All	0.161	0.788	.001	54	view →
COAD	OS	Tertile	All	0.140	0.806	<.001	54	view →
PAAD	OS	Tertile	All	0.131	0.613	.001	45	view →
STAD	OS	Tertile	IV	1.000	0.309	.034	27	view →

Pink = unfavorable, green = favorable. all 12 lineages →

RNU6-38P-ESCA (OS)

Kaplan–Meier survival curve for RNU6-38P RNA expression in ESCA: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with RNU6-38P in patient tissues and cancer cell lines. In patient samples, RNU6-38P shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	6,066	STAD (5941)	view →
RNA	3,229	LUSC (865)	view →