NAA38

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, NAA38 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated NAA38 data layer compared with 29 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in brain lower grade glioma (LGG), where higher NAA38 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated NAA38 expression acts as an unfavorable survival marker.

LGG, UCEC, and LIHC are the cancer types where NAA38 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LGGDFSMedianAll0.1720.845<.0019view →
UCECOSMedianIV0.2310.592.0366view →
LIHCOSMedianAll0.1880.669.0416view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

NAA38–LGG (DFS)

Kaplan–Meier survival curve for NAA38 mutant vs wild-type samples in LGG.

Open the LGG breakdown →

Exploration