NAA38

Across TCGA pan-cancer cohorts, NAA38 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of NAA38’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where NAA38 RNA is repressed in tumor relative to normal tissue. In most cancer types NAA38 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KICH, LIHC, and BRCA are the cancer types where NAA38 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NAA38 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	II,III,IV	−2.012	<.001	10	view →
LIHC	All	II,III,IV	+0.642	<.001	6	view →
BRCA	Female	All	+0.298	<.001	6	view →
HNSC	All	III,IV	+0.416	.011	5	view →
CHOL	Male	All	+1.554	<.001	4	view →
PAAD	Female	All	+0.564	.024	2	view →
UCEC	All	All	+0.519	.003	2	view →
COAD	Female	All	+0.456	.032	2	view →
BLCA	Female	All	+0.452	.033	2	view →
ESCA	All	All	+0.741	.025	1	view →
KIRP	All	II,III,IV	+0.395	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

NAA38–KICH

Open the KICH breakdown →