NAA35

Across TCGA pan-cancer cohorts, NAA35 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NAA35 data layer compared with 24 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher NAA35 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated NAA35 expression acts as an unfavorable survival marker, although some lineages such as LSCC and GBM show a favorable association.

LUAD, PDAC, and LSCC are the cancer types where NAA35 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Quartile	II,III,IV	0.286	0.765	.020	20	view →
PDAC	DFS	Quartile	III,IV	0.358	0.905	.006	13	view →
LSCC	DFS	Quartile	II,III,IV	0.874	0.474	.008	9	view →
GBM	DFS	Tertile	All	0.816	0.663	.025	4	view →
UCEC	DFS	Median	All	0.792	0.930	.030	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

NAA35–LUAD (OS)

Open the LUAD breakdown →