NAA35

Across TCGA patient cohorts, NAA35 mutation is significantly associated with the RNA expression of many other genes, with 4,397 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NAA35-associated genes across cancer lineages are OR12D1, CCDC163, and PLA2G4C-AS1. Each is linked with NAA35 in more than 1 cancer types. Because this analysis shows association rather than direction, both NAA35-to-partner and partner-to-NAA35 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR12D1 grouped by NAA35-low versus NAA35-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAA35→partner) and Y-score (partner→NAA35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	OR12D1 →	+0.108	+6.257	<.001	.001	3	2
UCEC	CCDC163 →	+0.489	+1.990	<.001	<.001	3	2
UCEC	PLA2G4C-AS1 →	-0.148	-2.796	.003	.001	3	2
SKCM	MIR921 →	+0.442	+4.159	<.001	.002	3	2
BRCA	RNU4-84P →	+0.306	+5.317	.003	.006	3	2
BRCA	RN7SKP117 →	+0.171	+4.995	.004	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,397 associations by consensus.

OR12D1 by NAA35 expression — READ

Explore this box plot interactively →