NAA35

Across TCGA patient cohorts, NAA35 mutation is significantly associated with the total protein of many other genes, with 54 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NAA35-associated genes across cancer lineages are ASNS, Caspase-7-cleavedD198, and S6_pS240_S244. Each is linked with NAA35 in more than 2 cancer types. Because this analysis shows association rather than direction, both NAA35-to-partner and partner-to-NAA35 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by NAA35-low versus NAA35-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAA35→partner) and Y-score (partner→NAA35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.352	+1.321	.003	.029	3	3
COAD	Caspase-7-cleavedD198 →	+1.009	+3.178	.009	.010	3	2
UCEC	S6_pS240_S244 →	+0.331	+2.222	.015	.010	3	2
UCEC	C-Raf →	+0.159	+2.502	<.001	.001	3	2
UCEC	eEF2 →	+0.277	+2.115	.020	.016	3	1
UCEC	EGFR_pY1068 →	-0.348	-2.584	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 54 associations by consensus.

ASNS by NAA35 expression — UCEC

Explore this box plot interactively →