NAA30

Across TCGA patient cohorts, NAA30 mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NAA30-associated genes across cancer lineages are EGFR_pY1068, eIF4E, and A-Raf_pS299. Each is linked with NAA30 in more than 1 cancer types. Because this analysis shows association rather than direction, both NAA30-to-partner and partner-to-NAA30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR_pY1068 grouped by NAA30-low versus NAA30-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAA30→partner) and Y-score (partner→NAA30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.269	-2.807	.014	.003	3	1
UCEC	eIF4E →	+0.209	+3.169	.023	.019	2	2
UCEC	A-Raf_pS299 →	-0.115	-2.321	.027	.034	3	1
UCEC	INPP4B →	-0.333	-2.321	.018	.034	3	1
UCEC	JNK_pT183_Y185 →	-0.245	-2.115	<.001	.017	3	1
UCEC	Ku80 →	+0.215	+2.128	.037	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

EGFR_pY1068 by NAA30 expression — UCEC

Explore this box plot interactively →