NAA30

Across TCGA pan-cancer cohorts, NAA30 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of NAA30’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where NAA30 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NAA30 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

HNSC, THCA, and KIRC are the cancer types where NAA30 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NAA30 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.369	<.001	10	view →
THCA	All	II,III,IV	−0.548	<.001	9	view →
KIRC	All	II,III,IV	−0.333	<.001	6	view →
LIHC	All	All	+0.311	.002	5	view →
LUSC	Male	All	+0.485	<.001	4	view →
CHOL	All	All	+0.681	<.001	3	view →
KIRP	Female	II,III,IV	+0.646	.005	2	view →
UCEC	All	All	−0.500	.015	2	view →
ESCA	All	All	+0.457	.025	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

NAA30–HNSC

Open the HNSC breakdown →