NAA11

Across TCGA patient cohorts, NAA11 protein abundance is significantly associated with the RNA expression of many other genes, with 3,340 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible NAA11-associated genes across cancer lineages are TLR4, ABCE1, and IFT81. Each is linked with NAA11 in more than 2 cancer types. Because this analysis shows association rather than direction, both NAA11-to-partner and partner-to-NAA11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NAA11 versus TLR4 in GBM, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAA11→partner) and Y-score (partner→NAA11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TLR4 →	-0.766	-0.381	<.001	.001	3	3
UCEC	ABCE1 →	+0.623	+0.327	.003	.005	3	3
OV	IFT81 →	+0.826	+0.591	.001	.002	3	2
PDAC	PTPRN2 →	-1.690	-0.515	<.001	<.001	3	2
OV	ARHGAP25 →	-0.690	-0.622	.006	<.001	3	2
PDAC	PLD4 →	-0.872	-0.437	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,340 associations by consensus.

NAA11 vs TLR4 — GBM

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