N4BP3

Across TCGA patient cohorts, N4BP3 protein abundance is significantly associated with the RNA expression of many other genes, with 946 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible N4BP3-associated genes across cancer lineages are KLHL30, TMEM38A, and TMEM30A. Each is linked with N4BP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both N4BP3-to-partner and partner-to-N4BP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, N4BP3 versus KLHL30 in UCEC, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (N4BP3→partner) and Y-score (partner→N4BP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KLHL30 →	+1.062	+0.788	.005	.001	3	2
UCEC	TMEM38A →	+1.283	+0.953	.008	.006	3	2
OV	TMEM30A →	-0.573	-0.854	.006	.002	3	1
OV	SLC35F5 →	-0.551	-0.807	<.001	.001	3	1
OV	GCG →	-0.078	-0.685	.003	<.001	3	1
OV	SFTPA1 →	-0.081	-0.941	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 946 associations by consensus.

N4BP3 vs KLHL30 — UCEC

Explore this scatter interactively →