N4BP3

Across TCGA patient cohorts, N4BP3 mutation is significantly associated with the RNA expression of many other genes, with 1,442 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible N4BP3-associated genes across cancer lineages are IGLJ5, TSPY16P, and RNU6-598P. Each is linked with N4BP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both N4BP3-to-partner and partner-to-N4BP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGLJ5 grouped by N4BP3-low versus N4BP3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (N4BP3→partner) and Y-score (partner→N4BP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGLJ5 →	+0.221	+2.478	<.001	.006	3	2
UCEC	TSPY16P →	+0.020	+4.481	<.001	.002	3	2
SKCM	RNU6-598P →	+0.234	+3.947	<.001	.002	3	2
SKCM	RNU6-905P →	+0.245	+4.098	<.001	.001	3	2
LUAD	RNU6-158P →	+0.512	+4.330	<.001	.002	3	2
LUAD	MIR4436B1 →	+0.403	+4.303	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,442 associations by consensus.

IGLJ5 by N4BP3 expression — UCEC

Explore this box plot interactively →