N4BP2L2

Across TCGA patient cohorts, N4BP2L2 mutation is significantly associated with the RNA expression of many other genes, with 6,975 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible N4BP2L2-associated genes across cancer lineages are NDUFA6, KCTD9, and NDUFS4. Each is linked with N4BP2L2 in more than 2 cancer types. Because this analysis shows association rather than direction, both N4BP2L2-to-partner and partner-to-N4BP2L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NDUFA6 grouped by N4BP2L2-low versus N4BP2L2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (N4BP2L2→partner) and Y-score (partner→N4BP2L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NDUFA6 →	+0.462	+1.680	<.001	<.001	3	3
UCEC	KCTD9 →	+0.677	+2.258	<.001	<.001	3	3
UCEC	NDUFS4 →	+0.393	+1.513	<.001	<.001	3	3
UCEC	CKS1BP6 →	+0.302	+1.391	<.001	<.001	3	3
UCEC	FCER1A →	-0.822	-2.478	<.001	<.001	3	2
UCEC	MYADM →	+0.531	+2.303	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,975 associations by consensus.

NDUFA6 by N4BP2L2 expression — UCEC

Explore this box plot interactively →