N4BP2L2

Across TCGA cell cohorts, N4BP2L2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,019 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible N4BP2L2-associated GO terms across cancer lineages are Negative regulation of hematopoietic stem cell differentiation, Regulation of cytoplasmic mRNA processing body assembly, and Positive regulation of cytoplasmic mRNA processing body assembly. Each is linked with N4BP2L2 in more than 18 cancer types. Because this analysis shows association rather than direction, both N4BP2L2-to-partner and partner-to-N4BP2L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of hematopoietic stem cell differentiation grouped by N4BP2L2-low versus N4BP2L2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (N4BP2L2→partner) and Y-score (partner→N4BP2L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of hematopoietic stem cell differentiation →	+0.195	+1.173	<.001	<.001	3	19
LUNG_SCLC	Regulation of cytoplasmic mRNA processing body assembly →	+0.168	+0.833	<.001	.001	3	15
UPPER_AERODIGESTIVE_TRACT	Positive regulation of cytoplasmic mRNA processing body assembly →	+0.135	+1.373	<.001	<.001	3	15
STOMACH	Protein ufmylation →	+0.122	+0.960	<.001	<.001	3	14
SOFT_TISSUE	Protein desumoylation →	+0.104	+0.690	<.001	<.001	3	14
OVARY	mRNA destabilization →	+0.063	+1.030	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,019 associations by consensus.

Negative regulation of hematopoietic stem cell differentiation by N4BP2L2 expression — OESOPHAGUS

Explore this box plot interactively →