N4BP2L2

Across TCGA cell cohorts, N4BP2L2 mutation is significantly associated with the RNA expression of many other genes, with 602 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible N4BP2L2-associated genes across cancer lineages are CD300H, PAX1, and DIRAS2. Each is linked with N4BP2L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both N4BP2L2-to-partner and partner-to-N4BP2L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD300H grouped by N4BP2L2-low versus N4BP2L2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (N4BP2L2→partner) and Y-score (partner→N4BP2L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CD300H →	+0.014	+2.415	<.001	.009	3	2
BLOOD_Leukemia	PAX1 →	+0.025	+4.060	.002	.003	3	1
BLOOD_Leukemia	DIRAS2 →	+0.124	+4.087	<.001	.009	3	1
BLOOD_Leukemia	TACR3 →	+0.028	+4.060	<.001	.003	3	1
BLOOD_Leukemia	SOX1 →	+0.515	+4.564	<.001	.001	3	1
BLOOD_Leukemia	GUCA2A →	+0.031	+4.384	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 602 associations by consensus.

CD300H by N4BP2L2 expression — LARGE_INTESTINE

Explore this box plot interactively →