N4BP2L2-IT2

Across TCGA pan-cancer cohorts, N4BP2L2-IT2 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated N4BP2L2-IT2 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher N4BP2L2-IT2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated N4BP2L2-IT2 expression acts as an unfavorable survival marker, although some lineages such as READ and SKCM show a favorable association.

KIRC, ACC, and READ are the cancer types where N4BP2L2-IT2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.495	0.698	<.001	69	view →
ACC	DFS	Median	All	0.455	0.698	.005	43	view →
READ	OS	Tertile	III,IV	0.833	0.234	.001	29	view →
LIHC	DFS	Quartile	All	0.399	0.636	<.001	27	view →
UVM	DFS	Quartile	III,IV	0.218	0.793	.010	26	view →
CESC	DFS	Tertile	All	0.387	0.679	.007	22	view →
SKCM	OS	Median	All	0.381	0.260	.003	17	view →
BRCA	OS	Median	III,IV	0.618	0.430	.010	17	view →
HNSC	OS	Quartile	II,III,IV	0.528	0.308	.018	17	view →
LGG	DFS	Tertile	All	0.784	0.866	.004	13	view →
GBM	DFS	Tertile	All	0.445	0.252	.023	6	view →
COAD	DFS	Quartile	III,IV	0.445	0.735	.023	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

N4BP2L2-IT2–KIRC (DFS)

Open the KIRC breakdown →