MZT2A

Across TCGA patient cohorts, MZT2A protein abundance is significantly associated with the RNA expression of many other genes, with 2,565 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible MZT2A-associated genes across cancer lineages are PPP4R3A, MANBAL, and CST3. Each is linked with MZT2A in more than 1 cancer types. Because this analysis shows association rather than direction, both MZT2A-to-partner and partner-to-MZT2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MZT2A versus PPP4R3A in PDAC, with a Pearson correlation of -0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MZT2A→partner) and Y-score (partner→MZT2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PPP4R3A →	-0.435	-0.330	.005	.003	3	2
LSCC	MANBAL →	+0.316	+0.322	.006	.006	3	2
BRCA	CST3 →	+0.605	+0.232	.008	.005	3	2
PDAC	ZNF430 →	-0.621	-0.454	.003	.001	3	2
PDAC	ZNF426 →	-0.504	-0.342	<.001	<.001	3	2
PDAC	ZNF827 →	-0.467	-0.352	.006	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,565 associations by consensus.

MZT2A vs PPP4R3A — PDAC

Explore this scatter interactively →