MZF1

Across TCGA patient cohorts, MZF1 mutation is significantly associated with the RNA expression of many other genes, with 1,096 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MZF1-associated genes across cancer lineages are PABPC1L2B-AS1, RN7SL314P, and RN7SL330P. Each is linked with MZF1 in more than 2 cancer types. Because this analysis shows association rather than direction, both MZF1-to-partner and partner-to-MZF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PABPC1L2B-AS1 grouped by MZF1-low versus MZF1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MZF1→partner) and Y-score (partner→MZF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PABPC1L2B-AS1 →	+0.015	+4.734	<.001	.002	3	3
CESC	RN7SL314P →	+0.101	+4.984	.008	.003	3	2
BLCA	RN7SL330P →	+0.259	+3.642	<.001	.009	3	2
SKCM	RNU7-113P →	+0.579	+3.160	.002	.006	3	2
SKCM	RNU7-119P →	+0.351	+4.302	<.001	.007	3	2
COAD	RNA5SP237 →	+0.382	+3.670	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,096 associations by consensus.

PABPC1L2B-AS1 by MZF1 expression — COAD

Explore this box plot interactively →