MZF1-AS1

Across TCGA pan-cancer cohorts, MZF1-AS1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated MZF1-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MZF1-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MZF1-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LAML show a favorable association.

KIRC, ACC, and LGG are the cancer types where MZF1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	All	0.490	0.724	.001	79	view →
ACC	DFS	Tertile	All	0.418	0.791	<.001	60	view →
LGG	DFS	Median	All	0.630	0.847	<.001	46	view →
KIRP	DFS	Tertile	IV	0.156	0.588	.004	33	view →
MESO	DFS	Tertile	III,IV	0.234	0.439	.006	24	view →
PRAD	DFS	Median	All	0.699	0.862	<.001	20	view →
HNSC	DFS	Tertile	III,IV	0.417	0.288	.017	19	view →
COAD	DFS	Median	All	0.723	0.832	.008	18	view →
LAML	DFS	Tertile	All	0.563	0.315	.025	18	view →
CHOL	DFS	Median	IV	0.251	0.794	.010	15	view →
CESC	DFS	Quartile	All	0.649	0.825	.008	14	view →
LUAD	DFS	Tertile	IV	0.445	0.896	.012	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

MZF1-AS1–KIRC (DFS)

Open the KIRC breakdown →