Across TCGA patient cohorts, MYT1L mutation is significantly associated with the RNA expression of many other genes, with 7,177 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYT1L-associated genes across cancer lineages are TIPIN, CDC7, and OBI1. Each is linked with MYT1L in more than 5 cancer types. Because this analysis shows association rather than direction, both MYT1L-to-partner and partner-to-MYT1L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYT1L→partner) and Y-score (partner→MYT1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TIPIN →	+0.462	+1.636	<.001	<.001	3	6
LUAD	CDC7 →	+0.610	+2.819	<.001	<.001	3	6
LUSC	OBI1 →	+0.310	+2.724	.001	.002	3	5
SKCM	SUPV3L1 →	+0.327	+1.802	<.001	<.001	3	5
UCEC	C12orf43 →	+0.200	+1.286	<.001	<.001	3	5
LUSC	FANCC →	+0.422	+2.538	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,177 associations by consensus.

Exploration

MYT1L survival (RNA) · tumor vs normal (RNA) · all MYT1L data types