Across TCGA cell cohorts, MYT1L RNA expression is significantly associated with the go_rna of many other GO terms, with 1,891 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MYT1L-associated GO terms across cancer lineages are Regulation of RNA polymerase II transcription preinitiation complex assembly, Regulation of transcription initiation by RNA polymerase II, and Regulation of transcription of nucleolar large rRNA by RNA polymerase I. Each is linked with MYT1L in more than 4 cancer types. Because this analysis shows association rather than direction, both MYT1L-to-partner and partner-to-MYT1L results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYT1L→partner) and Y-score (partner→MYT1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Regulation of RNA polymerase II transcription preinitiation complex assembly →	+0.115	+0.779	<.001	.002	3	5
BLOOD_Leukemia	Regulation of transcription initiation by RNA polymerase II →	+0.040	+0.510	<.001	.008	3	5
LUNG_SCLC	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.060	+1.859	.008	.006	2	5
LUNG_SCLC	Polyol metabolic process →	-0.058	-2.631	<.001	.001	3	4
LUNG_SCLC	tRNA transcription by RNA polymerase III →	+0.075	+2.174	.002	.002	2	5
LUNG_SCLC	Error-free translesion synthesis →	+0.087	+2.400	.002	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,891 associations by consensus.

Exploration

MYT1L survival (RNA) · tumor vs normal (RNA) · all MYT1L data types