MYT1L

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MYT1L mutation is significantly associated with the RNA expression of many other genes, with 666 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MYT1L-associated genes across cancer lineages are PSMG2, MINPP1, and NPRL2. Each is linked with MYT1L in more than 2 cancer types. Because this analysis shows association rather than direction, both MYT1L-to-partner and partner-to-MYT1L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYT1L→partner) and Y-score (partner→MYT1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEPSMG2 →+0.361+1.714.008.00633
LARGE_INTESTINEMINPP1 →+0.469+2.000.004.00932
LARGE_INTESTINENPRL2 →+0.438+3.404<.001<.00132
LARGE_INTESTINETATDN2 →+0.377+2.000.008.00932
LARGE_INTESTINEHIPK4 →+0.059+2.301.001.00232
LARGE_INTESTINEHESX1 →+0.464+2.043<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 666 associations by consensus.

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