MYRF

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MYRF RNA expression is significantly associated with the protein abundance of many other proteins, with 16,598 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MYRF-associated proteins across cancer lineages are PLEKHA6_S777, RASAL1, and SPTAN1. Each is linked with MYRF in more than 4 cancer types. Because this analysis shows association rather than direction, both MYRF-to-partner and partner-to-MYRF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MYRF versus PLEKHA6_S777 in PDAC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MYRF→partner) and Y-score (partner→MYRF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PDACPLEKHA6_S777 →+1.276+0.981<.001<.00135
GBMRASAL1 →+0.831+1.362<.001<.00135
GBMSPTAN1 →+0.309+0.989<.001<.00134
GBMSH3BGRL2 →+0.548+1.252<.001<.00134
PDACABLIM1 →+0.331+0.767<.001<.00134
BRCASSRP1 →+0.368+0.590<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,598 associations by consensus.

MYRF vs PLEKHA6_S777 — PDAC

Per-sample scatter of MYRF vs PLEKHA6_S777 in PDAC (Pearson r = 0.43).

Explore this scatter interactively →

Exploration