MYPOP

Across TCGA cell cohorts, MYPOP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,217 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MYPOP-associated GO terms across cancer lineages are Negative regulation of calcium ion export across plasma membrane, Regulation of protein localization to centrosome, and Regulation of protein localization to endoplasmic reticulum. Each is linked with MYPOP in more than 15 cancer types. Because this analysis shows association rather than direction, both MYPOP-to-partner and partner-to-MYPOP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of calcium ion export across plasma membrane grouped by MYPOP-low versus MYPOP-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYPOP→partner) and Y-score (partner→MYPOP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of calcium ion export across plasma membrane →	+0.086	+0.796	<.001	<.001	3	16
BONE	Regulation of protein localization to centrosome →	+0.107	+0.656	.003	.001	3	14
KIDNEY	Regulation of protein localization to endoplasmic reticulum →	+0.129	+0.446	.002	.008	3	14
BONE	Positive regulation of protein localization to centrosome →	+0.133	+0.543	<.001	.001	3	13
OESOPHAGUS	Negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.088	+0.602	.003	.003	3	13
UPPER_AERODIGESTIVE_TRACT	Regulation of calcium ion export across plasma membrane →	+0.109	+0.700	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,217 associations by consensus.

Negative regulation of calcium ion export across plasma membrane by MYPOP expression — BONE

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