MYPN

Across TCGA patient cohorts, MYPN RNA expression is significantly associated with the protein abundance of many other proteins, with 10,976 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MYPN-associated proteins across cancer lineages are MCU, PAF1, and ASH2L. Each is linked with MYPN in more than 3 cancer types. Because this analysis shows association rather than direction, both MYPN-to-partner and partner-to-MYPN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MYPN versus MCU in GBM, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MYPN→partner) and Y-score (partner→MYPN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MCU →	+0.387	+0.204	<.001	<.001	3	4
BRCA	PAF1 →	-0.180	-0.388	.001	.004	3	4
HNSC	ASH2L →	-0.219	-1.124	<.001	<.001	3	3
HNSC	BRD2 →	-0.197	-1.095	<.001	.003	3	3
GBM	CAMK2G →	+0.272	+0.094	.001	.003	3	3
HNSC	CRAT →	+0.660	+1.739	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,976 associations by consensus.

MYPN vs MCU — GBM

Explore this scatter interactively →