MYPN

Across TCGA cell cohorts, MYPN RNA expression is significantly associated with the go_rna of many other GO terms, with 2,946 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible MYPN-associated GO terms across cancer lineages are Regulation of protein localization to mitochondrion, Positive regulation of focal adhesion assembly, and Negative regulation of cardiac muscle adaptation. Each is linked with MYPN in more than 9 cancer types. Because this analysis shows association rather than direction, both MYPN-to-partner and partner-to-MYPN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to mitochondrion grouped by MYPN-low versus MYPN-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYPN→partner) and Y-score (partner→MYPN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of protein localization to mitochondrion →	+0.075	+1.017	.001	.001	3	10
STOMACH	Positive regulation of focal adhesion assembly →	+0.188	+0.274	<.001	.006	3	9
BREAST	Negative regulation of cardiac muscle adaptation →	+0.281	+1.225	<.001	<.001	3	9
BREAST	Negative regulation of cardiac muscle hypertrophy in response to stress →	+0.281	+1.225	<.001	<.001	3	9
URINARY_TRACT	Thyroid hormone catabolic process →	+1.565	+1.028	<.001	<.001	3	9
BREAST	Positive regulation of supramolecular fiber organization →	+0.063	+1.047	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,946 associations by consensus.

Regulation of protein localization to mitochondrion by MYPN expression — BREAST

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