MYOZ2

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MYOZ2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,944 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MYOZ2-associated proteins across cancer lineages are SYNPO2, LIMS2, and LMOD1. Each is linked with MYOZ2 in more than 8 cancer types. Because this analysis shows association rather than direction, both MYOZ2-to-partner and partner-to-MYOZ2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MYOZ2 versus SYNPO2 in HNSC, with a Pearson correlation of 0.83.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MYOZ2→partner) and Y-score (partner→MYOZ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCSYNPO2 →+1.118+2.257<.001<.00139
UCECLIMS2 →+0.979+0.514<.001<.00137
UCECLMOD1 →+1.313+0.487<.001<.00137
UCECPRKG1 →+0.782+0.369<.001.00827
UCECLMOD1_S85 →+1.710+0.488<.001<.00136
UCECTNS1 →+0.979+0.573<.001<.00127
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,944 associations by consensus.

MYOZ2 vs SYNPO2 — HNSC

Per-sample scatter of MYOZ2 vs SYNPO2 in HNSC (Pearson r = 0.83).

Explore this scatter interactively →

Exploration