MYOG

Across TCGA patient cohorts, MYOG mutation is significantly associated with the total protein of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYOG-associated genes across cancer lineages are IGFBP2, AMPK_pT172, and Ku80. Each is linked with MYOG in more than 1 cancer types. Because this analysis shows association rather than direction, both MYOG-to-partner and partner-to-MYOG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGFBP2 grouped by MYOG-low versus MYOG-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYOG→partner) and Y-score (partner→MYOG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGFBP2 →	-0.887	-3.321	.009	.010	3	1
UCEC	AMPK_pT172 →	+0.513	+3.335	.017	.005	3	1
UCEC	Ku80 →	+0.283	+3.009	.022	.019	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

IGFBP2 by MYOG expression — UCEC

Explore this box plot interactively →