MYOG

Across TCGA pan-cancer cohorts, MYOG RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of MYOG’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MYOG RNA is repressed in tumor relative to normal tissue. In most cancer types MYOG is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, KICH, and UCEC are the cancer types where MYOG tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MYOG RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	−0.073	<.001	10	view →
KICH	All	All	−0.107	<.001	6	view →
UCEC	All	All	+0.125	.031	2	view →
HNSC	Male	IV	−2.295	.045	1	view →
KIRP	Male	All	−0.097	.033	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

MYOG–KIRC

Open the KIRC breakdown →