MYOG

Across TCGA cell cohorts, MYOG RNA expression is significantly associated with the go_rna of many other GO terms, with 2,010 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible MYOG-associated GO terms across cancer lineages are Regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum, Negative regulation of glutamate secretion, and Regulation of neurotrophin production. Each is linked with MYOG in more than 4 cancer types. Because this analysis shows association rather than direction, both MYOG-to-partner and partner-to-MYOG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum grouped by MYOG-low versus MYOG-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYOG→partner) and Y-score (partner→MYOG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum →	-0.194	-5.241	<.001	<.001	3	5
LUNG_NSCLC_LUAD	Negative regulation of glutamate secretion →	+1.450	+0.007	<.001	.007	3	5
LUNG_NSCLC_LUAD	Regulation of neurotrophin production →	+0.905	+0.007	<.001	.009	3	5
SOFT_TISSUE	Embryonic hemopoiesis →	-0.103	-3.135	<.001	<.001	3	5
UPPER_AERODIGESTIVE_TRACT	Regulation of protein localization to cell periphery →	+0.049	+0.019	.005	.001	3	4
OVARY	Phosphatidylinositol 3-kinase/protein kinase B signal transduction →	+0.056	+0.036	.008	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,010 associations by consensus.

Regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum by MYOG expression — SOFT_TISSUE

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