MYOC

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MYOC RNA expression is significantly associated with the protein abundance of many other proteins, with 11,092 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible MYOC-associated proteins across cancer lineages are SYNPO2_S363, CAVIN2, and EHD2. Each is linked with MYOC in more than 5 cancer types. Because this analysis shows association rather than direction, both MYOC-to-partner and partner-to-MYOC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MYOC versus SYNPO2_S363 in HNSC, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MYOC→partner) and Y-score (partner→MYOC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCSYNPO2_S363 →+1.156+0.674<.001<.00136
BRCACAVIN2 →+0.847+0.327<.001<.00136
BRCAEHD2 →+0.600+0.299<.001<.00136
BRCAPLIN4 →+1.477+0.558<.001<.00136
BRCAPPP1R12B_S947 →+1.125+0.525<.001.00436
BRCAOGN →+1.250+0.462<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,092 associations by consensus.

MYOC vs SYNPO2_S363 — HNSC

Per-sample scatter of MYOC vs SYNPO2_S363 in HNSC (Pearson r = 0.49).

Explore this scatter interactively →

Exploration