MYO9B

Across TCGA cell cohorts, MYO9B mutation is significantly associated with the RNA expression of many other genes, with 1,819 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MYO9B-associated genes across cancer lineages are KIF2C, ZFAND4, and SFPQ. Each is linked with MYO9B in more than 3 cancer types. Because this analysis shows association rather than direction, both MYO9B-to-partner and partner-to-MYO9B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KIF2C grouped by MYO9B-low versus MYO9B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO9B→partner) and Y-score (partner→MYO9B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	KIF2C →	+0.488	+2.458	.003	<.001	3	4
BLOOD_Leukemia	ZFAND4 →	+1.200	+3.199	<.001	.007	3	4
LARGE_INTESTINE	SFPQ →	+0.391	+2.649	.001	.001	3	3
LARGE_INTESTINE	CEP85 →	+0.617	+3.523	.003	<.001	3	3
LARGE_INTESTINE	DNMT1 →	+0.507	+3.237	.006	.003	3	3
LARGE_INTESTINE	ZBED3 →	+0.812	+2.458	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,819 associations by consensus.

KIF2C by MYO9B expression — LARGE_INTESTINE

Explore this box plot interactively →