MYO9A

Across TCGA patient cohorts, MYO9A protein abundance is significantly associated with the RNA expression of many other genes, with 9,045 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MYO9A-associated genes across cancer lineages are PRPF19, CDC20, and POC1A. Each is linked with MYO9A in more than 3 cancer types. Because this analysis shows association rather than direction, both MYO9A-to-partner and partner-to-MYO9A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MYO9A versus PRPF19 in UCEC, with a Pearson correlation of -0.23.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO9A→partner) and Y-score (partner→MYO9A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PRPF19 →	-0.400	-0.172	.001	.003	3	4
UCEC	CDC20 →	-1.156	-0.232	.002	<.001	3	4
UCEC	POC1A →	-0.861	-0.180	.003	.005	3	4
CCRCC	NEGR1 →	+1.169	+0.212	<.001	.001	3	4
BRCA	E2F2 →	-0.673	-0.258	.001	<.001	3	4
BRCA	CALHM5 →	+0.774	+0.315	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,045 associations by consensus.

MYO9A vs PRPF19 — UCEC

Explore this scatter interactively →