MYO1G

Across TCGA cell cohorts, MYO1G mutation is significantly associated with the RNA expression of many other genes, with 692 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MYO1G-associated genes across cancer lineages are CGRRF1, N4BP1, and RAB3IP. Each is linked with MYO1G in more than 1 cancer types. Because this analysis shows association rather than direction, both MYO1G-to-partner and partner-to-MYO1G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CGRRF1 grouped by MYO1G-low versus MYO1G-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO1G→partner) and Y-score (partner→MYO1G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CGRRF1 →	+0.524	+3.608	.005	.001	3	2
BLOOD_Leukemia	N4BP1 →	+0.505	+3.548	.005	.001	3	2
BLOOD_Leukemia	RAB3IP →	+1.262	+3.489	<.001	.001	3	2
BLOOD_Leukemia	ASPHD2 →	+0.761	+3.321	.002	.005	3	2
BLOOD_Leukemia	KIF3A →	+1.199	+3.321	<.001	.005	3	2
BLOOD_Leukemia	TIFA →	+1.126	+3.489	.004	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 692 associations by consensus.

CGRRF1 by MYO1G expression — BLOOD_Leukemia

Explore this box plot interactively →