MYO1D

Across TCGA patient cohorts, MYO1D mutation is significantly associated with the RNA expression of many other genes, with 3,838 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYO1D-associated genes across cancer lineages are MIR3663, TRDD1, and HARS1. Each is linked with MYO1D in more than 3 cancer types. Because this analysis shows association rather than direction, both MYO1D-to-partner and partner-to-MYO1D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3663 grouped by MYO1D-low versus MYO1D-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO1D→partner) and Y-score (partner→MYO1D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MIR3663 →	+0.299	+4.327	<.001	.009	3	4
BRCA	TRDD1 →	+0.682	+7.473	<.001	.007	3	3
UCEC	HARS1 →	+0.236	+2.113	.001	<.001	3	3
UCEC	RIOK2 →	+0.337	+1.680	<.001	<.001	3	3
UCEC	P4HA1 →	+0.593	+1.523	<.001	<.001	3	3
CESC	RNU6-1191P →	+0.806	+4.103	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,838 associations by consensus.

MIR3663 by MYO1D expression — HNSC

Explore this box plot interactively →