MYO1D

Across TCGA patient cohorts, MYO1D mutation is significantly associated with the total protein of many other genes, with 42 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYO1D-associated genes across cancer lineages are ATM, Caspase-7-cleavedD198, and eIF4E. Each is linked with MYO1D in more than 2 cancer types. Because this analysis shows association rather than direction, both MYO1D-to-partner and partner-to-MYO1D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by MYO1D-low versus MYO1D-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO1D→partner) and Y-score (partner→MYO1D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.652	-3.379	<.001	<.001	3	3
COAD	Caspase-7-cleavedD198 →	+0.921	+2.815	.034	.036	3	3
UCEC	eIF4E →	+0.166	+1.637	.007	.001	3	2
UCEC	PCNA →	+0.175	+1.807	.005	.003	3	2
UCEC	TFRC →	+0.385	+1.415	.013	.040	3	2
UCEC	ASNS →	+0.300	+1.662	.004	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

ATM by MYO1D expression — UCEC

Explore this box plot interactively →