MYO1D

Across TCGA cell cohorts, MYO1D mutation is significantly associated with the RNA expression of many other genes, with 379 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MYO1D-associated genes across cancer lineages are REG3G, GPR174, and SFT2D3. Each is linked with MYO1D in more than 2 cancer types. Because this analysis shows association rather than direction, both MYO1D-to-partner and partner-to-MYO1D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, REG3G grouped by MYO1D-low versus MYO1D-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO1D→partner) and Y-score (partner→MYO1D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	REG3G →	+0.040	+5.452	<.001	<.001	3	3
URINARY_TRACT	GPR174 →	+0.358	+4.700	.007	.001	3	2
URINARY_TRACT	SFT2D3 →	+0.574	+3.807	.004	.005	3	2
BLOOD_Leukemia	LYG1 →	+0.652	+3.470	<.001	.002	3	2
BLOOD_Leukemia	SGCB →	+1.472	+3.351	<.001	.003	3	2
BLOOD_Leukemia	STOX1 →	+0.725	+3.215	.004	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 379 associations by consensus.

REG3G by MYO1D expression — BLOOD_Lymphoma

Explore this box plot interactively →