Across TCGA patient cohorts, MYO1C mutation is significantly associated with the RNA expression of many other genes, with 3,004 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYO1C-associated genes across cancer lineages are SLC35A4, DHDDS, and SLC25A51. Each is linked with MYO1C in more than 2 cancer types. Because this analysis shows association rather than direction, both MYO1C-to-partner and partner-to-MYO1C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO1C→partner) and Y-score (partner→MYO1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SLC35A4 →	+0.277	+2.692	.002	<.001	3	3
UCEC	DHDDS →	+0.332	+1.966	<.001	.002	3	3
UCEC	SLC25A51 →	+0.331	+2.458	.003	.001	3	3
COAD	APCDD1 →	-1.547	-3.584	.001	.002	3	3
UCEC	RPL23AP82 →	+0.454	+2.233	<.001	<.001	3	3
UCEC	C19orf54 →	+0.356	+1.847	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,004 associations by consensus.

Exploration

MYO1C survival (RNA) · tumor vs normal (RNA) · all MYO1C data types