Across TCGA cell cohorts, MYO1C mutation is significantly associated with the RNA expression of many other genes, with 417 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MYO1C-associated genes across cancer lineages are DNASE2B, STMND1, and LYG1. Each is linked with MYO1C in more than 2 cancer types. Because this analysis shows association rather than direction, both MYO1C-to-partner and partner-to-MYO1C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO1C→partner) and Y-score (partner→MYO1C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	DNASE2B →	+0.090	+3.584	.005	.004	3	3
CNS	STMND1 →	+0.293	+3.337	<.001	.007	3	2
LARGE_INTESTINE	LYG1 →	+1.126	+3.364	<.001	.002	3	2
BLOOD_Leukemia	C16orf92 →	+0.160	+3.037	<.001	.001	3	2
BLOOD_Leukemia	ENO4 →	+0.108	+2.758	<.001	.006	3	2
BLOOD_Leukemia	KHDC3L →	+0.186	+3.359	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 417 associations by consensus.

Exploration

MYO1C survival (RNA) · tumor vs normal (RNA) · all MYO1C data types