Across TCGA cell cohorts, MYO18A mutation is significantly associated with the RNA expression of many other genes, with 690 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MYO18A-associated genes across cancer lineages are LRIT3, OR5C1, and MIOX. Each is linked with MYO18A in more than 2 cancer types. Because this analysis shows association rather than direction, both MYO18A-to-partner and partner-to-MYO18A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO18A→partner) and Y-score (partner→MYO18A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	LRIT3 →	+0.152	+1.936	.003	.005	3	3
BLOOD_Myeloma	OR5C1 →	+0.023	+4.807	<.001	.006	3	2
BLOOD_Leukemia	MIOX →	+0.306	+3.228	<.001	.004	3	2
BLOOD_Leukemia	FAM149A →	+0.681	+2.824	.003	.001	3	2
BLOOD_Leukemia	C12orf57 →	+0.819	+2.730	.009	.001	3	2
BLOOD_Leukemia	DSE →	+0.784	+2.730	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 690 associations by consensus.

Exploration

MYO18A survival (RNA) · tumor vs normal (RNA) · all MYO18A data types