MYO15B

Across TCGA patient cohorts, MYO15B mutation is significantly associated with the RNA expression of many other genes, with 3,462 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYO15B-associated genes across cancer lineages are LINC00686, RN7SL97P, and IGHD4-4. Each is linked with MYO15B in more than 1 cancer types. Because this analysis shows association rather than direction, both MYO15B-to-partner and partner-to-MYO15B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00686 grouped by MYO15B-low versus MYO15B-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYO15B→partner) and Y-score (partner→MYO15B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	LINC00686 →	+0.701	+5.411	<.001	<.001	3	2
CESC	RN7SL97P →	+0.123	+4.559	<.001	.006	3	2
SARC	IGHD4-4 →	+1.340	+5.778	<.001	.003	3	2
SARC	PIEZO1P1 →	+0.203	+6.380	<.001	.001	3	2
UCEC	NDUFAF2P1 →	+0.511	+2.008	<.001	.001	3	1
UCEC	LINC01943 →	+0.384	+1.254	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,462 associations by consensus.

LINC00686 by MYO15B expression — CESC

Explore this box plot interactively →