MYLK-AS2

Across TCGA pan-cancer cohorts, MYLK-AS2 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated MYLK-AS2 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher MYLK-AS2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MYLK-AS2 expression acts as an unfavorable survival marker, although some lineages such as PAAD and LGG show a favorable association.

UCEC, KICH, and ACC are the cancer types where MYLK-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	All	0.555	0.682	<.001	88	view →
KICH	OS	Tertile	II,III,IV	0.339	0.922	.001	84	view →
ACC	OS	Tertile	III,IV	0.390	0.821	<.001	69	view →
MESO	OS	Median	II,III,IV	0.289	0.485	.005	63	view →
LIHC	DFS	Tertile	II,III,IV	0.188	0.394	.004	45	view →
KIRC	OS	Quartile	II,III,IV	0.322	0.588	<.001	39	view →
STAD	OS	Quartile	All	0.258	0.610	<.001	32	view →
CHOL	OS	Tertile	IV	0.024	0.732	.014	18	view →
PAAD	DFS	Tertile	All	0.417	0.220	.011	17	view →
CESC	OS	Quartile	All	0.698	0.823	.012	16	view →
LGG	OS	Median	All	0.857	0.759	.001	14	view →
UCS	OS	Median	II,III,IV	0.535	0.239	.024	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

MYLK-AS2–UCEC (DFS)

Open the UCEC breakdown →