MYLIP

Across TCGA patient cohorts, MYLIP mutation is significantly associated with the RNA expression of many other genes, with 1,649 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYLIP-associated genes across cancer lineages are RN7SL134P, IGLJCOR18, and FAM32DP. Each is linked with MYLIP in more than 1 cancer types. Because this analysis shows association rather than direction, both MYLIP-to-partner and partner-to-MYLIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL134P grouped by MYLIP-low versus MYLIP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYLIP→partner) and Y-score (partner→MYLIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL134P →	+0.121	+2.097	<.001	.005	3	2
UCEC	IGLJCOR18 →	+0.366	+2.363	<.001	<.001	3	2
UCEC	FAM32DP →	+0.075	+3.508	<.001	.002	3	2
ESCA	SSXP1 →	+0.350	+5.247	<.001	.006	3	2
ESCA	RNU6-535P →	+0.817	+5.450	<.001	.004	3	2
ESCA	MIR617 →	+0.641	+5.954	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,649 associations by consensus.

RN7SL134P by MYLIP expression — UCEC

Explore this box plot interactively →