MYLIP

Across TCGA pan-cancer cohorts, MYLIP RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of MYLIP’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where MYLIP RNA is repressed in tumor relative to normal tissue. In most cancer types MYLIP is over-expressed in tumor, although a few such as KICH and LUAD show the opposite, repressed pattern.

KICH, LUAD, and LIHC are the cancer types where MYLIP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MYLIP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	II,III,IV	−1.468	<.001	10	view →
LUAD	Female	II,III,IV	−1.158	<.001	9	view →
LIHC	Female	All	+1.117	<.001	7	view →
KIRP	All	All	−0.415	.001	7	view →
UCEC	All	All	−0.969	<.001	6	view →
CHOL	All	All	+2.800	<.001	5	view →
LUSC	Male	All	−0.805	<.001	5	view →
THCA	All	All	−0.385	.010	5	view →
BRCA	Female	All	−0.362	<.001	4	view →
KIRC	All	All	+0.347	<.001	4	view →
STAD	All	All	+0.443	.038	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

MYLIP–KICH

Open the KICH breakdown →